Upper Ohio and Wheeling Creek
Wheeling Creek is a tributary of the Ohio River, 25 miles (40 km) long, in the Northern Panhandle of West Virginia in the United States, with a watershed extending into southwestern Pennsylvania. Via the Ohio River, it is part of the watershed of the Mississippi River, draining an area of approximately 300 square miles (780 km©&Mac247;) on the unglaciated portion of the Allegheny Plateau. It flows into the Ohio River in downtown Wheeling, just downstream of Ohio's Wheeling Creek on the opposite bank.[6] According to the Geographic Names Information System, it has also been known as Big Wheeling Creek.[1]

Some of the featured rivers and streams of the Upper Ohio and Wheeling Creek Watershed are:
- Wheeling Creek
- Ohio River
- Middle Island Creek